Obesity or overweight is a frequent problem faced by anyone in any hemisphere. A recent study claims to have discovered the genes that makes you fat. DNA is predicted that control other genes found in body fat cells.
The researchers said the results of this research is expected to help the handling of obesity-related diseases such as heart disease and diabetes. The group of scientists identified a gene called KLF14 are associated with type 2 diabetes and cholesterol levels, but they have not found the rule of the gene.
Researchers analyzed more than 20ribu gene in fat samples taken under the skin of 800 British female twin brothers.
Found the relationship between gene KLF14 with the level of genes found in fatty tissue, suggesting that KLF14 acts as a controller (controller). These findings confirm 600 fat samples obtained from several groups of people from Iceland.
The study published in the journal Nature Genetics, reveal that fat plays an important role in affecting one’s metabolism disorders such as obesity. heart disease, and diabetes. The drugs may be developed to target this gene regulation.
Tim Spector of King’s College London who led the study, said this discovery is a major study that shows that any small changes that occur in one of the key regulatory genes could lead to chaos and bad effect on the metabolism of other genes.
One in ten people worldwide, nearly half a billion people, are obese. This phenomenon has increased twofold since the 1980s.
In America, diseases related to obesity health spend nearly 10 percent of the total budget of approximately 147 billion dollars per year. Nearly two-thirds, about 62 percent, from adults in Britain are overweight or obese. Diabetes type 2, which is usually associated with poor diet and lack of exercise, touch the level of the portion of the epidemic.
In his report, as reported by Dailymail, researchers explained that other genes controlled by KLF14 found associated with a range of metabolic characteristics, including body mass index (bmi), obesity, cholesterol, insulin, and glucose levels.
Mark McCarthy of Oxford University who was involved in the study said KLF14 seems to act as a master switch controlling or controlling major changes in the behavior change process that connects the liver and muscle fat disorders that contribute to diabetes and other conditions.
“We are trying to understand this process and how can use that information to improve the treatment of this condition,” concluded McCarthy.
